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AKT1 mutation

Showing 1 - 25 of 7,365
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Bile Acids in Acute Insulin Resistance

Recruiting
  • PI3K Gene Mutation
  • +4 more
  • Drug-induced acute insulin resistance due to PI3K inhibitor, AKT inhibitor, or mTOR inhibitor
  • New York, New York
    Columbia University Medical Center
Oct 6, 2022

Triple Negative Breast Cancer, Metastatic Breast Cancer, Mutation Trial in Shanghai (Everolimus, Investigator's Choice of

Not yet recruiting
  • Triple Negative Breast Cancer
  • +2 more
  • Shanghai, Shanghai, China
    Fudan University Shanghai Cancer Center
Jul 25, 2023

Solid Tumor, ARID1A Gene Mutation Trial in Greenville (Tazemetostat)

Suspended
  • Solid Tumor
  • ARID1A Gene Mutation
  • Greenville, South Carolina
    Prisma Health Cancer Institute
Jan 10, 2023

AXIN1 Gene Mutation, APC Gene Mutation, Solid Tumor Trial (REC-4881)

Not yet recruiting
  • AXIN1 Gene Mutation
  • +2 more
  • (no location specified)
Aug 21, 2023

Breast Cancer, Prostate Cancer, Advanced Solid Tumors Trial in Middletown, Harrison, New York (AZD5363, Enzalutamide,

Active, not recruiting
  • Breast Cancer
  • +2 more
  • Middletown, New Jersey
  • +2 more
Jul 5, 2022

Aumolertinib, Anlotinib, TP53 Trial (Aumolertinib,Anlotinib)

Not yet recruiting
  • Aumolertinib
  • +4 more
  • (no location specified)
Mar 8, 2023

Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Not yet recruiting
  • Autosomal Dominant Optic Atrophy
  • +3 more
    • Sydney, Australia
      Sydney Eye Hospital
    Nov 15, 2023

    Gene Mutation Trial in Beijing (RAG-17)

    Enrolling by invitation
    • Gene Mutation
    • Beijing, China
      Beijing Tiantan Hospital
    Jun 11, 2023

    An Intervention to Increase Genetic Testing in Families Who May

    Recruiting
    • BRCA1 Mutation
    • +21 more
    • Intervention Arm At-risk Relative/ARR Contacts
    • +5 more
    • Basking Ridge, New Jersey
    • +7 more
    Nov 22, 2022

    Advanced Solid Malignancy, Safety and Tolerability, Pharmacokinetics Trial in Worldwide (AZD5363)

    Active, not recruiting
    • Advanced Solid Malignancy
    • +13 more
    • Los Angeles, California
    • +33 more
    Dec 22, 2022

    Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma Trial in United States

    Completed
    Has Results
    • Endometrial Adenocarcinoma
    • +4 more
    • Akt Inhibitor MK2206
    • Laboratory Biomarker Analysis
    • Boston, Massachusetts
    • +6 more
    Jan 13, 2022

    Metastatic Solid Tumor, SF3B1 Gene Mutation, Spliceosome Mutation Trial in Baltimore (Recommendation for treatment with

    Recruiting
    • Metastatic Solid Tumor
    • +4 more
    • Recommendation for treatment with immunotherapy
    • Baltimore, Maryland
      Johns Hopkins University
    Sep 8, 2022

    Cholangiocarcinoma Non-resectable, Cholangiocarcinoma Metastatic Trial (Ivosidenib)

    Not yet recruiting
    • Cholangiocarcinoma Non-resectable
    • Cholangiocarcinoma Metastatic
    • (no location specified)
    Oct 10, 2023

    Non Small Cell Lung Cancer, Immune Checkpoint Inhibitor, EGFR Exon 21 Mutation Trial in Peking (Pembrolizumab, pemetrexed,

    Not yet recruiting
    • Non Small Cell Lung Cancer
    • +2 more
    • Peking, China
      Peking Union Medical College Hospital
    Nov 16, 2023

    Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression = 1% and an STK11

    Recruiting
    • Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
    • Montpellier, France
    • +7 more
    Dec 19, 2022

    NSCLC Metastatic Trial in Stockholm (Stereotactic body radiation therapy (SBRT), Temporary Stopping)

    Recruiting
    • Non-small Cell Lung Cancer Metastatic
    • Stereotactic body radiation therapy (SBRT)
    • Temporary Stopping
    • Stockholm, Solna, Sweden
      Karolinska University Hospital
    Nov 9, 2023

    Retinal Dystrophy, PRPF31 Mutationassociated Retinal Dystrophy, RP11 Trial in Dallas (VP-001)

    Recruiting
    • Retinal Dystrophy
    • +2 more
    • Dallas, Texas
      Retina Foundation of the Southwest
    Jun 5, 2023

    Advanced Malignant Solid Tumor, EGFR Gene Amplification, EGFR Gene Mutation Trial in Houston (Everolimus, Neratinib,

    Recruiting
    • Advanced Malignant Solid Neoplasm
    • +9 more
    • Houston, Texas
      M D Anderson Cancer Center
    Oct 25, 2022

    Breast Cancer, Genetic Predisposition Trial in Rome, Varese (Genetic predisposition to breast cancer)

    Recruiting
    • Breast Cancer
    • Genetic Predisposition
    • Genetic predisposition to breast cancer
    • Rome, Italy
    • +1 more
    May 4, 2023

    BRCA1/2 Flu Vaccine

    Active, not recruiting
    • BRCA1 Mutation
    • BRCA2 Mutation
    • Seasonal influenza vaccine
    • Philadelphia, Pennsylvania
      University of Pennsylvania
    Aug 16, 2022

    Everolimus-containing Chemotherapy in HER2- mBC PI3K/AKT/mTOR

    Completed
    • Breast Cancer
    • +2 more
    • No intervention, it was a retrospective study.
    • Hangzhou, Zhejiang, China
      Zhejiang Cancer Hospital
    Sep 13, 2021

    BRCA1 Gene Mutation, BRCA2 Gene Mutation, Ovarian Serous Adenocarcinoma Trial in Buffalo, New York (biological, other, drug)

    Active, not recruiting
    Has Results
    • BRCA1 Gene Mutation
    • +5 more
    • Durvalumab
    • +3 more
    • Buffalo, New York
    • +1 more
    Jan 20, 2023

    Advanced Solid Tumors Trial (INCB099280, adagrasib)

    Not yet recruiting
    • Advanced Solid Tumors
    • (no location specified)
    Sep 8, 2023

    Solid Tumor, Advanced Solid Tumor, NSCLC Trial (MRTX1133)

    Not yet recruiting
    • Solid Tumor
    • +4 more
    • (no location specified)
    Feb 21, 2023

    Recurrent IDH1/2 Mutated Glioma Trial in Paris (Azacitidine)

    Recruiting
    • Recurrent IDH1/2 Mutated Glioma
    • Paris, France
      Pitie Salpetriere Hospital
    Aug 29, 2022